Mammary Cancer in Mice
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چکیده
منابع مشابه
Granulopoiesis and thrombopoiesis in mice bearing transplanted mammary cancer.
Growth of a transplantable mammary cancer in CE mice (CE 1460 MA CA) was paralleled by hyperplasia of the granulocytic elements of the bone marrow and peripheral leukocytosis (up to 350,000 leukocytes/cu mm) with a lymphoid-myeloid ratio re versal to 1:4 and a shift to the left. About 5-20% of the granulo cytic elements in the blood and bone marrow showed morpho logic abnormalities. Hematocrit ...
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Microvascular changes in the mammary gland in mice during pregnancy and lactation were investigated by scanning electron microscopy (SEM) with a corrosion cast method, tvansmission e]eetron microscopy (TEM) and morphometry. By SEM, duct-associated capillary plexuses were sparsety distributed to branch into adipocytes during virgin period. With advance in pregnancy, both branches from the capMar...
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It has been made clear by recent investigations that the presence of the mammary tumor agent (MTA) is not necessary for the development of mammary carcinoma in mice; the MTA is assumed to act only as an accelerator or intensifier. Thus, hormonal factors in the genesis of this type of tumor in mice have been recently emphasized, although it is realized that various other factors are involved as ...
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Heterozygous female mice carrying a targeted mutation of the Ets2 transcription factor gene were mated with a mouse strain that develops mammary tumors due to the expression of the polyoma virus middle T oncogene. Tumors from females with only one wild-type Ets2 gene were approximately one-half the size of tumors from controls. The smaller size of the tumors was correlated with a more different...
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BACKGROUND:Canine mammary gland cancers are the most prevalent malignancies in dogs. There are different challenges regarding management of these cancers in dogs and human, one hypothesis is related to small cellular subset of tumor mass called cancer stem cell. These cells are therapy resistant and cause metastasis and relapse even after primary successful treatment. The well-identified phenot...
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ژورنال
عنوان ژورنال: Nature
سال: 1945
ISSN: 0028-0836,1476-4687
DOI: 10.1038/156787a0